1. Cook pasta according to package directions. Meanwhile, in large nonstick pan, heat olive oil over medium heat. Add pepper flakes and cook 30 seconds; stir in garlic and cook 1 minute more. Add V8 juice, increase heat to high, and bring mixture to a boil.
2. Reduce heat to low, and add grape tomatoes. Cook 4 minutes. Stir in tuna, lemon juice, butter, and basil. Toss with pasta. If you have leftovers, stir at room temperature the next day.