Heat oven to 350°F. Grease a 13 x 9 x 2-inch baking dish.
Combine ziti, sweet pepper, cheeses, tomatoes, salt and pepper in bowl. Pour into prepared dish. Pour in half-and-half. Cover.
Bake at 350°F for 30 minutes. Uncover; top with crumbs. Bake 30 minutes until crusty and bubbly.