Coat slow-cooker bowl with nonstick cooking spray. Stir in tomatoes, onion, carrot, garlic, oregano, sugar, salt and red pepper flakes. Crumble in ground turkey and stir to combine.
Cover and cook on HIGH for 6 hours or LOW for 8 hours.
Stir in Cooking Creme until evenly incorporated into sauce. Stir half of sauce into cooked pasta; serve remaining sauce on the side. Garnish with basil, if desired.