Pregnancy My Pregnant Body Is it save to take pain relievers during pregnancy? By Parents Editors Parents Editors The Parents Editors byline means there is an experienced group of editors and journalists behind the scenes of the article. Learn more about the Parents team, our core values, and editorial guidelines. our editorial guidelines Published on July 2, 2015 Share Tweet Pin Email Q: Is it safe to take pain medications like Tylenol or Advil during pregnancy? A: If you've been sidelined by a headache, a cold compress and a solid nap often does the trick. But if you need additional relief, it's important to choose your pain medication wisely. Acetaminophen (the main ingredient in Tylenol) is safe for moms-to-be when used as directed. However, you should avoid aspirin and ibuprofen (found in Advil, Motrin, and Nuprin). Studies have suggested that taking these medications near conception or in early pregnancy may increase your risk of miscarriage and birth defects. Answered by American Baby Team Was this page helpful? Thanks for your feedback! Tell us why! Other Submit