Anti-Nausea Drug Safe for Pregnancy, Study Finds

One in 10 pregnant women has nausea and vomiting bad enough to need medicine but many forgo it out of fear of side effects. No drugs are currently approved for morning sickness in the United States although doctors are free to prescribe whatever they believe is best.

Zofran, sold by GlaxoSmithKline and in generic form for treating nausea from cancer treatments and other causes, has been the top choice. Yet women and doctors have been leery of it because a small study previously suggested it might raise the risk of a birth defect — cleft palate.

The new study of more than 600,000 pregnancies in Denmark found no evidence of major birth-related problems, so women should not be afraid to use Zofran if they need it, said Dr. Iffath Hoskins, a high-risk pregnancy specialist at NYU Langone Medical Center and a spokeswoman for the American College of Obstetricians and Gynecologists.

"It's effective and it's safe," she said. "Nobody is giving you a gold star for suffering through this."

Poor nutrition because of excessive vomiting can harm the woman and the fetus, she said.

Image: Woman with morning sickness, via Shutterstock

1 Comment

  1. During my first pregnancy, I was so sick that I was placed on the generic form of Zofran. Zofran and its generic alternatives are now linked to a variety of birth defects, so that's no longer an option... and I was a little worried how to curb with my morning sickness. Fortunately, I found a natural remedy called "No to Morning Sickness Tea" which was a lifesaver. I spent my days without getting sick.

Parents may receive compensation when you click through and purchase from links contained on this website.