From the Irish surname Cathasaigh. Known for John Luther "Casey" Jones, the locomotive engineer who died in 1900 saving the lives of passengers on the "Cannonball Express." He was born in Cayce, Kentucky, where he received his nickname. He was immortalized in a folk song. Also known for Baseball Hall of Famer Charles Dillon "Casey" Stengel. He was given the nickname, "Casey," from the initials for Kansas City, Missouri, where he was born. A unisex name.