Cons may include not being able to have pain medication if you feel you need it, and, if you midwife doesn't have hospital privileges or a solid backup relationship with an OB who does, it won't be ideal in case of an emergency. That said, many complications can be handled by a midwife at home, and if not chances are she will suggest transferring to the hospital before it becomes an emergency. Be sure to ask questions when you interview midwives about what kind of equipment she brings with her, reasons for transferring and doctor backup.
Another con to think about is whether or not homebirth midwives are licensed or recognized in your state. Many midwives practice "underground" and you'll have to decide if you're comfortable with that or not.
Whether you choose home or hospital birth this time around, be sure to ask providers all the questions that may be important to you so you can make an informed decision. Good luck!