Many everyday childhood illnesses are becoming increasingly hard to treat. You've probably heard about MRSA -- methicillin-resistant Staphylococcus aureus, potentially deadly bacteria that don't respond to commonly used antibiotics. A new study analyzing data from more than 300 hospitals found that there's been an alarming increase in MRSA-caused ear, sinus, and throat infections in children.
However, the problem isn't limited to one superbug. Two-year-old Sloane Poth, of Charlotte, North Carolina, needed surgery last year for a skin infection caused by another strain of drug-resistant bacteria. On Monday, it looked like diaper rash. By Friday, she was in the hospital. "She's fine now, but it was very scary," says her father, Michael. "The surgeon said that he's now seeing two or three serious cases like hers every week."
Although most antibiotic-resistant infections aren't necessarily life-threatening, pediatricians who can't use their first-choice antibiotic may have to prescribe a drug that's not approved for children or simply isn't kid-friendly. "If medicine doesn't taste good, children won't swallow it, and then your only option is to give them a shot," says Mika Hiramatsu, MD, a pediatrician in Castro Valley, California. For MRSA, however, there are no outpatient shots that work, so a child who won't take oral antibiotics will need to be hospitalized for IV antibiotics. "It's a huge ordeal for the types of infections that would have been very easy for us to cure 20 years ago," says Dr. Hiramatsu.
Treating a resistant infection is also costly in terms of both time and money -- not to mention anxiety and lost sleep. Karyn Bilezerian's 16-month-old son, Karson, suffered from a painful ear infection for nearly a month until his fourth antibiotic finally did the trick. "Every week, we were going back to the doctor and the pharmacy," says Bilezerian, who lives in Wrentham, Massachusetts. "Karson had never needed antibiotics before, so I was shocked when the first three didn't work. With the fourth one, we saw a difference very quickly -- when it worked, it worked."The Path of Most Resistance
Every child has colonies of helpful and harmful bacteria living in his body. Within those colonies, a few individual strains of bacteria may have a natural ability to resist certain antibiotics. So whenever your child takes an antibiotic, the germs that are susceptible to that drug die, leaving more room for the drug-resistant microbes to reproduce and become dominant. The same thing can happen when your child doesn't finish his whole course of antibiotics. Either way, the strong survive.
If your child develops a sizable population of resistant bacteria after taking an antibiotic, it doesn't necessarily mean she'll become ill. The new bugs may simply live in her body -- in which case, she's said to be "colonized" -- or they may disappear over time. Under the right circumstances, though, she could get sick with a tough-to-treat infection. One of the great mysteries of medical science is why bacterial infections develop in one case and not another; it probably depends on a variety of factors, such as the strength and number of bacteria, and the child's own immune system.
However, even if your child doesn't have any symptoms, she can still pass along those resistant bacteria to others. That's how a child who's never even taken antibiotics can become infected with drug-resistant bacteria. "Young kids in childcare centers share germs better than they share toys," says Sarah Long, MD, a pediatric infectious-disease specialist at St. Christopher's Hospital for Children, in Philadelphia.
In fact, kids play a key role in the development of resistant bacteria -- not only do they spread germs easily, but they take more antibiotics than adults do. While many of those prescriptions are crucial for their health, others are unnecessary. "Antibiotics are important for treating bacterial infections, but more than 90 percent of children's illnesses are actually viral infections that can't be cured with antibiotics," says Dr. Long. Asking for antibiotics when your child has a bad cold, for example, can wind up doing more harm than good.
Part of the problem is that pediatricians sometimes prescribe antibiotics simply because parents want them to. In one CDC study, parents walked away with a prescription 65 percent of the time if the doctor thought they expected one, but only 12 percent of the time otherwise. "Although some physicians are getting the message, it's still a problem," says Lauri Hicks, DO, medical director of the CDC program Get Smart: Know When Antibiotics Work. Earlier this year, the CDC also sent letters to several chain pharmacies expressing concern about their programs that were offering customers free generic antibiotics as the solution for colds and flu. Officials worried this would increase pressure on doctors to prescribe antibiotics inappropriately.
Let's face it: As parents, we typically put our child's immediate well-being -- and sometimes our own need to get back to work -- ahead of a remote concept like bacterial evolution. If there's a chance antibiotics will make our child feel better, we may be tempted to take it. However, antibiotic resistance is not a problem we can worry about tomorrow. Kids are already at risk when they get the following seemingly run-of-the-mill illnesses, so it's important to know when antibiotics don't make sense.