Posts Tagged ‘ age ’

Older Dads May Have Kids with Greater Mental Illness Risk

Thursday, February 27th, 2014

Mental illnesses, including schizophrenia, autism, and attention deficit hyperactivity disorder (ADHD), may be more common in children born to fathers who are “middle aged,” or age 45 and older, according to new research conducted in Sweden.  The New York Times has more:

In recent years, scientists have debated based on mixed evidence whether a father’s age is linked to his child’s vulnerability to individual disorders like autism and schizophrenia. Some studies have found strong associations, while others have found weak associations or none at all.

The new report, which looked at many mental disorders in Sweden, should inflame the debate, if not settle it, experts said. Men have a biological clock of sorts because of random mutations in sperm over time, the report suggests, and the risks associated with later fatherhood may be higher than previously thought. The findings were published on Wednesday in the journal JAMA Psychiatry.

“This is the best paper I’ve seen on this topic, and it suggests several lines of inquiry into mental illness,” said Dr. Patrick F. Sullivan, a professor of genetics at the University of North Carolina, who was not involved in the research. “But the last thing people should do is read this and say, ‘Oh no, I had a kid at 43, the kid’s doomed.’ The vast majority of kids born to older dads will be just fine.”

Dr. Kenneth S. Kendler, a professor of psychiatry and human molecular genetics at Virginia Commonwealth University, also urged caution in interpreting the results. “This is great work from a scientific perspective,” he said. “But it needs to be replicated, and biomedical science needs to get in gear and figure out what accounts for” the mixed findings of previous studies.

The strengths of the new report are size and rigor. The research team, led by Brian M. D’Onofrio of Indiana University, analyzed medical and public records of some 2.6 million people born in Sweden from 1973 to 2001. Like many European countries, Sweden has centralized medical care and keeps detailed records, so the scientists knew the father’s age for each birth and were able to track each child’s medical history over time, as well as that of siblings and other relatives. Among other things, the analysis compared the mental health of siblings born to the same father and found a clear pattern of increased risk with increasing paternal age.

Compared with the children of young fathers, aged 20 to 24, those born to men age 45 and older had about twice the risk of developing psychosis, the signature symptom of schizophrenia; more than three times the likelihood of receiving a diagnosis of autism; and about 13 times the chance of having a diagnosis of attention deficit disorder. Children born to older fathers also tended to struggle more with academics and substance abuse.

The researchers controlled for every factor they could think of, including parents’ education and income. Older couples tend to be more stable and have more income — both protective factors that help to temper mental problems — and this was the case in the study. But much of the risk associated with paternal age remained.

“We spent months trying to make the findings go away, looking at the mother’s age, at psychiatric history, doing sub-analyses,” Dr. D’Onofrio said. “They wouldn’t go away.”

Use our growth chart for help calculating your child’s height and weight percentiles.

Treating Children with Psychiatric Disorders
Treating Children with Psychiatric Disorders
Treating Children with Psychiatric Disorders

Image: Older dad, via Shutterstock

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Poll: Women Should Have Kids Earlier than Men

Wednesday, November 13th, 2013

A recent Gallup poll has found that they a majority of Americans believe that age 25 or younger is the ideal time for women to start a family, while men should wait until they are age 26 or older.  More from Today.com:

The majority of Americans, 58 percent, believe the ideal age for women to start having children is 25 or younger, while the majority, 52 percent, said men should start having children at 26 or older, a recent Gallup poll found.

The average perceived ideal age for each gender to have children differs only slightly: 25 for women and 27 for men, Gallup found. Some 5,100 U.S. adults took part in the survey.

Gallup acknowledged “tension between biology and societal norms” in the results, noting young women may have the best odds of conceiving a healthy child but that rushing to become a parent “doesn’t square with modern Western sensibilities about pursuing higher education and career goals, finding the perfect partner, or simply relishing the experience of young adulthood.”

Gallup also found “significant differences by education and race” in the poll. The proportion of respondents saying the ideal time for a woman to have her first child by age 25 was greater among blacks and Hispanics than among whites.

Image: Expectant couple, via Shutterstock

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